Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487101 | 0.84 | P4HTM (0.50) | MAPK1P4HTMKDM4EL3MBTL1KMT2A | |
| SCHEMBL29260502 | 0.80 | MAPK1 (0.61) | MAPK1P4HTMMAPTRAB9AKDM4E | |
| SCHEMBL31359497 | 0.76 | MAPK1 (0.65) | MAPK1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL721291 | 0.76 | MAPK1 (0.65) | MAPK1MAPTKDM4EL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL14125808 | 0.75 | MAPK1 (0.62) | MAPK1MAPTKDM4EL3MBTL1LMNA | |
| SCHEMBL9621696 | 0.74 | P4HTM (0.57) | MAPK1P4HTMKDM4EL3MBTL1 | |
| SCHEMBL4251561 | 0.74 | NAMPT (0.50) | P4HTMNAMPTKMT2A | |
| SCHEMBL3235643 | 0.72 | MAPK1 (0.46) | MAPK1KDM4EL3MBTL1PTGS1LMNA | |
| SCHEMBL22242767 | 0.71 | LMNA (0.58) | P4HTMMAPTRAB9AKDM4EPTGS1 | |
| SCHEMBL27212642 | 0.71 | P2RX7 (0.52) | MAPTRAB9AKDM4EL3MBTL1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839371-A | HYPOTENSIVE AGENTS, DIURETICS, VASODILATORS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |