Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845099 | 0.79 | DRD2 (0.54) | DRD2DRD3PRKCIMTNR1AMTNR1B | |
| SCHEMBL10574411 | 0.79 | DRD2 (0.54) | DRD2DRD3PRKCIMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL10577359 | 0.78 | DRD2 (0.52) | DRD2DRD3MTNR1AMTNR1B | |
| SCHEMBL10487260 | 0.78 | DRD2 (0.46) | DRD2DRD3PRKCIDYRK1APIK3CA | |
| Hydrochloric Acid SCHEMBL10487255 | 0.78 | DRD2 (0.52) | DRD2DRD3MTNR1AMTNR1B | |
| SCHEMBL10487375 | 0.76 | DRD2 (0.48) | DRD2DRD3PRKCIMTNR1AMTNR1B | |
| SCHEMBL10487367 | 0.74 | DRD2 (0.52) | DRD2DRD3PRKCIDYRK1APIK3CA | |
| SCHEMBL984492 | 0.71 | PRKCI (0.48) | DRD2DRD3PRKCIDYRK1ADYRK2 | |
| SCHEMBL23519758 | 0.70 | DRD2 (0.55) | DRD2DRD3PRKCIDYRK1APIK3CA | |
| SCHEMBL25086433 | 0.70 | DRD2 (0.48) | DRD2DRD3PRKCIDYRK1APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874878-A | CHEMICAL INTERMEDIATES FOR ANTIDEPRESSANTS | ADIR ET CIE (FR) | 1989-10-17 | — | — | US | disclosed |
| US-4851429-A | ANTIDEPRESSANT, TRANQUILIZERS | ADIR ET CIE (FR) | 1989-07-25 | — | — | US | disclosed |