Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781359 | 0.80 | — | — | |
| SCHEMBL5344420 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL5413587 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL3825323 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL22534064 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL6425835 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL10487355 | 0.71 | KDM4E (0.35) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL16857570 | 0.69 | ALDH1A1 (0.39) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL16857571 | 0.69 | ALDH1A1 (0.39) | KDM4EALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL11038408 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1HTTNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874878-A | CHEMICAL INTERMEDIATES FOR ANTIDEPRESSANTS | ADIR ET CIE (FR) | 1989-10-17 | — | — | US | disclosed |
| US-4851429-A | ANTIDEPRESSANT, TRANQUILIZERS | ADIR ET CIE (FR) | 1989-07-25 | — | — | US | disclosed |