Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 6/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857570 | 1.00 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2MIFMTNR1A | |
| SCHEMBL20695760 | 0.72 | ALDH1A1 (0.52) | ALDH1A1POLBSMN1; SMN2MIFMTNR1A | |
| SCHEMBL10487295 | 0.69 | KDM4E (0.38) | ALDH1A1KDM4ERAB9AHTTNCOA1 | |
| SCHEMBL8137564 | 0.65 | MTNR1A (0.50) | ALDH1A1POLBSMN1; SMN2MIFMTNR1A | |
| SCHEMBL13523759 | 0.64 | CCR2 (0.45) | — | |
| SCHEMBL5413587 | 0.63 | KDM4E (0.43) | ALDH1A1CA2KDM4ERAB9AHTT | |
| SCHEMBL5344420 | 0.63 | KDM4E (0.43) | ALDH1A1CA2KDM4ERAB9AHTT | |
| SCHEMBL3825323 | 0.63 | KDM4E (0.43) | ALDH1A1CA2KDM4ERAB9AHTT | |
| SCHEMBL13861685 | 0.62 | ALDH1A1 (0.79) | ALDH1A1POLBSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL629852 | 0.62 | EPHX1 (0.56) | ALDH1A1POLBSMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889378-B1 | METHOD FOR PRODUCING HYDROXY-L-LYSINE EMPLOYING AN L-LYSINE HYDROXYLASE AND METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID | API CORP (JP) | 2018-01-10 | — | — | EP | disclosed |
| US-9512452-B2 | L-lysine hydroxylase and production method for hydroxy-L-lysine and hydroxy-L-pipecolic acid using same | API CORPORATION (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20150259715-A1 | L-Lysine Hydroxylase and Production Method for Hydroxy-L-Lysine and Hydroxy-L-Pipecolic Acid Using Same | API CORPORATION (JP) | 2015-09-17 | — | — | US | disclosed |
| EP-2889378-A1 | PRODUCTION METHOD FOR L-LYSINE HYDROXYLASE AND HYDROXY-L-LYSINE USING SAME, AND PRODUCTION METHOD FOR HYDROXY-L-PIPECOLIC ACID | API Corporation (JP) | 2015-07-01 | — | — | EP | disclosed |