Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815784 | 0.92 | THRA (0.41) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL10815786 | 0.92 | THRA (0.41) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL10487302 | 0.85 | THRA (0.37) | THRATHRBPTGS2ALOX5 | |
| SCHEMBL11271584 | 0.81 | MAPK1 (0.42) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL29000694 | 0.81 | THRA (0.39) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL29000676 | 0.81 | THRA (0.39) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL10487305 | 0.80 | THRA (0.43) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL6849772 | 0.79 | THRA (0.59) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL8393505 | 0.79 | THRA (0.59) | THRATHRBLIPGPTGS2ALOX5 | |
| SCHEMBL1100557 | 0.79 | THRA (0.59) | THRATHRBLIPGPTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814367-A | DISCOLORATION INHIBITION | ARGUS CHEMICAL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |