Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487304 | 0.85 | THRA (0.42) | THRATHRBALOX5PTGS2 | |
| SCHEMBL10815786 | 0.84 | THRA (0.41) | THRATHRBALOX5PTGS2 | |
| SCHEMBL10815784 | 0.84 | THRA (0.41) | THRATHRBALOX5PTGS2 | |
| SCHEMBL10487305 | 0.84 | THRA (0.43) | THRATHRBALOX5PTGS2 | |
| SCHEMBL29000694 | 0.83 | THRA (0.39) | THRATHRBALOX5PTGS2 | |
| SCHEMBL29000676 | 0.83 | THRA (0.39) | THRATHRBALOX5PTGS2 | |
| SCHEMBL10487314 | 0.82 | THRA (0.41) | THRATHRBALOX5PTGS2CYP3A4 | |
| SCHEMBL10816668 | 0.82 | THRA (0.41) | THRATHRBALOX5PTGS2CYP3A4 | |
| SCHEMBL11061944 | 0.81 | ALDH1A1 (0.36) | CYP2D6 | |
| SCHEMBL268679 | 0.80 | THRA (0.50) | THRATHRBALOX5PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814367-A | DISCOLORATION INHIBITION | ARGUS CHEMICAL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |