Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208530 | 0.87 | PARP10 (0.50) | PARP10L3MBTL1LMNASMN1; SMN2KCNQ3 | |
| SCHEMBL979843 | 0.87 | TTR (0.64) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9539594 | 0.87 | PARP10 (0.53) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL10703394 | 0.85 | PARP10 (0.51) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28128705 | 0.84 | PARP10 (0.67) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8752172 | 0.82 | TTR (0.50) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL29174197 | 0.81 | TTR (0.54) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8848427 | 0.81 | CES1 (0.49) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9804234 | 0.81 | TTR (0.43) | PARP10TTRL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9804251 | 0.81 | TTR (0.43) | PARP10TTRL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252592-A1 | Halogenated diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-13 | — | — | EP | claimed |
| US-4870218-A | Trihalobenzene compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-26 | — | — | US | disclosed |
| US-4788349-A | Halogenated diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-29 | — | — | US | disclosed |
| EP-0252592-A1 | Halogenated diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-13 | — | — | EP | disclosed |
| EP-0024611-B1 | PROCESS FOR PREPARING SUBSTITUTED BENZALDEHYDES | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| EP-0049911-A2 | Process for preparing alpha-hydroxybenzylphosphonic-acid esters | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
| US-4294762-A | ESTERIFICATION, DEPHOSPHORIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| EP-0024611-A1 | Process for preparing substituted benzaldehydes | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0020988-A2 | Process for preparing alpha-cyano-benzyl esters; intermediates therefor and their preparation | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |