Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.67 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289581 | 0.87 | PARP10 (0.67) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL3643463 | 0.87 | PARP10 (0.67) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL979843 | 0.87 | TTR (0.64) | PARP10TTRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9539594 | 0.87 | PARP10 (0.53) | PARP10TTRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10703394 | 0.85 | PARP10 (0.51) | PARP10TTRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10487356 | 0.84 | PARP10 (0.50) | PARP10TTRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11700754 | 0.82 | PARP10 (0.61) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL8848427 | 0.81 | CES1 (0.49) | PARP10TTRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29174197 | 0.81 | TTR (0.54) | PARP10TTRALDH1A1KMT2ALMNA | |
| SCHEMBL21697477 | 0.80 | PARP10 (0.54) | PARP10PARP15PARP14TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610140-B | 3-amine acylhydrazone derivative, preparation method and application of 3-amine acylhydrazone derivative | 青岛农业大学 | 2017-01-25 | — | — | CN | disclosed |