SCHEMBL979843

SCHEMBL979843

O=C(O)c1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.64
AKR1C3 P42330 1/20 0.56
PARP10 Q53GL7 1/20 0.53
SRD5A2 P31213 3/20 0.51
LPAR1 Q92633 3/20 0.50
LPAR5 Q9H1C0 3/20 0.50
LMNA P02545 2/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
MRGPRX4 Q96LA9 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NR1H4 Q96RI1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9539594 0.90 PARP10 (0.53) TTRPARP10SRD5A2LPAR1LPAR5
SCHEMBL10703394 0.88 PARP10 (0.51) TTRAKR1C3PARP10SRD5A2LPAR1
SCHEMBL10487356 0.87 PARP10 (0.50) TTRPARP10SRD5A2LPAR1LPAR5
SCHEMBL28128705 0.87 PARP10 (0.67) TTRPARP10LMNASMN1; SMN2L3MBTL1
SCHEMBL3130872 0.86 TTR (0.68) TTRAKR1C3PARP10SRD5A2LPAR1
SCHEMBL8848427 0.84 CES1 (0.49) TTRPARP10LPAR1LPAR5LMNA
SCHEMBL29174197 0.84 TTR (0.54) TTRPARP10LMNARAB9ASMN1; SMN2
SCHEMBL11462504 0.84 TTR (0.81) TTRAKR1C3PARP10SRD5A2RAB9A
SCHEMBL10799090 0.83 PARP10 (0.47) TTRAKR1C3PARP10SRD5A2LPAR1
SCHEMBL11051862 0.83 PARP10 (0.47) TTRPARP10LPAR1LPAR5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116338026-A Liquid chromatography tandem mass spectrometry detection method for detecting pesticides and metabolites thereof in protein-containing body fluid 华南农业大学 2023-06-27 CN claimed
WO-2023005682-A1 METHOD FOR ANALYZING TARGETED EXPOSURE GROUP OF ENVIRONMENTAL POLLUTANTS IN PLASMA, AND USE THEREOF 暨南大学 2023-02-02 WO claimed
CN-111721856-B Method for detecting pyrethroid pesticide metabolite in tea 中国农业科学院茶叶研究所 2022-12-13 CN claimed
CN-114813992-A Method for detecting phenols, esters and pesticide intermediates in urine 上海交通大学医学院 2022-07-29 CN claimed
CN-113671068-A Method for analyzing environmental pollutant targeting exposure component in blood plasma and application thereof 暨南大学 2021-11-19 CN claimed
CN-111721856-A Method for detecting pyrethroid pesticide metabolite in tea 中国农业科学院茶叶研究所 2020-09-29 CN claimed
US-20140030741-A1 In Vitro Method for Determining Presence of Type II Pyrethroids GIVAUDAN S.A. (CH) 2014-01-30 US claimed
EP-2642851-A1 IN VITRO METHOD FOR DETERMINING PRESENCE OF TYPE II PYRETHROIDS Givaudan SA (CH) 2013-10-02 EP claimed
CN-103298337-A In vitro method for determining presence of type II pyrethroids GIVAUDAN SA 2013-09-11 CN claimed
WO-2012069571-A1 IN VITRO METHOD FOR DETERMINING PRESENCE OF TYPE II PYRETHROIDS GIVAUDAN SA (CH) 2012-05-31 WO claimed
EP-0017882-A1 Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid BAYER AG (DE) 1980-10-29 EP claimed
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed
CN-117310025-A Method for screening key metabolites and pathways of ketosis based on double-platform metabolome 宁夏大学 2023-12-29 CN disclosed
EP-0048375-A1 Process for the preparation of 3-bromo-4-fluoro-benzoic acid BAYER AG (DE) 1982-03-31 EP disclosed
EP-0024516-A1 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom BAYER AG (DE) 1981-03-11 EP disclosed
EP-0017882-A1 Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid BAYER AG (DE) 1980-10-29 EP disclosed
EP-0017882-A1 Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid BAYER AG (DE) 1980-10-29 EP disclosed
EP-0017882-A1 Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid BAYER AG (DE) 1980-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S TTR 193/4885AKR1C3 547/4885PARP10 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.