Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | MLYCD | O95822 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539594 | 0.84 | PARP10 (0.53) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL979843 | 0.84 | TTR (0.64) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10703394 | 0.83 | PARP10 (0.51) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10487356 | 0.81 | PARP10 (0.50) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL28128705 | 0.81 | PARP10 (0.67) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL29174197 | 0.79 | TTR (0.54) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7248002 | 0.79 | CES1 (0.67) | CES1PARP10MLYCDSMN1; SMN2 | |
| SCHEMBL11051862 | 0.78 | PARP10 (0.47) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10799090 | 0.78 | PARP10 (0.47) | PARP10TTRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8848201 | 0.78 | AKR1C3 (0.66) | CES1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623103-B1 | PROCESS FOR PRODUCING TRIFLUOROMETHYL KETONES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-09-03 | — | — | EP | disclosed |
| US-5608062-A | Process for preparing trifluoromethyl ketones | HOECHST SCHERING AGREVO GMBH (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0623103-A1 | PROCESS FOR PRODUCING TRIFLUOROMETHYL KETONES. | HOECHST SCHERING AGREVO GMBH (DE) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014054-A1 | PROCESS FOR PRODUCING TRIFLUOROMETHYL KETONES | HOECHST SCHERING AGREVO GMBH (DE) | 1993-07-22 | — | — | WO | disclosed |
| US-5223536-A | Pyrethroid-like pesticides | FMC CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |