Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622351 | 0.86 | CTSK (0.36) | SYKCTSKCYP2D6CA1CA2 | |
| SCHEMBL30732632 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2CTSKCYP2D6CA1CA2 | |
| SCHEMBL30732806 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2CTSKCYP2D6CA1CA2 | |
| SCHEMBL10487647 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2CTSKCYP2D6CA1CA2 | |
| SCHEMBL5199242 | 0.82 | CASP1 (0.40) | CASP1 | |
| SCHEMBL210068 | 0.82 | CTSK (0.39) | SMN1; SMN2CTSKCYP2D6CA1CA2 | |
| SCHEMBL16564865 | 0.82 | CTSK (0.39) | SMN1; SMN2CTSKCYP2D6CA1CA2 | |
| SCHEMBL210067 | 0.82 | CTSK (0.39) | SMN1; SMN2CTSKCYP2D6CA1CA2 | |
| SCHEMBL4520424 | 0.79 | CA1 (0.38) | SYKCTSKCYP2D6CA1CA2 | |
| SCHEMBL7346754 | 0.79 | CA1 (0.38) | SYKCTSKCYP2D6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824974-A | Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarboxylic acid | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-25 | — | — | US | claimed |