Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LGMN | Q99538 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487576 | 0.91 | CTSK (0.48) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10493760 | 0.89 | CTSK (0.44) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10885728 | 0.79 | CTSK (0.48) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10493796 | 0.76 | ACE (0.49) | MEN1LMNAKMT2ACYP3A4 | |
| SCHEMBL10493706 | 0.75 | ACE (0.46) | MEN1LMNAKMT2ACYP3A4 | |
| SCHEMBL10487543 | 0.75 | CTSK (0.55) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10487573 | 0.75 | MEN1 (0.58) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL18359408 | 0.75 | MEN1 (0.58) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10795035 | 0.75 | CTSK (0.50) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10658290 | 0.75 | CTSK (0.59) | CTSKCTSLCTSBCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820729-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |