Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 8/20 | 0.55 |
| ▸ | CTSL | P07711 | 5/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.55 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | LGMN | Q99538 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18359408 | 1.00 | MEN1 (0.58) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL7325639 | 0.90 | CTSL (0.57) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL10487540 | 0.88 | MEN1 (0.63) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL13673300 | 0.87 | CTSL (0.50) | MEN1LMNAKMT2ACTSLCTSB | |
| SCHEMBL10487768 | 0.85 | MEN1 (0.60) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL8155357 | 0.84 | CTSL (0.56) | CTSKCTSLCTSBCTSSSIRT2 | |
| SCHEMBL1883119 | 0.81 | PIN1 (0.51) | MEN1LMNAKMT2APIN1 | |
| SCHEMBL10795035 | 0.80 | CTSK (0.50) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL17807555 | 0.80 | PIN1 (0.44) | MEN1LMNAKMT2APIN1 | |
| SCHEMBL18368249 | 0.80 | MEN1 (0.47) | MEN1LMNAKMT2ACTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820729-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |