Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130209 | 0.99 | CTSK (0.49) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10487578 | 0.95 | CTSK (0.53) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL7331321 | 0.90 | ELANE (0.56) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL10790451 | 0.89 | CTSK (0.54) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL7332393 | 0.89 | ELANE (0.56) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL10658214 | 0.89 | CTSK (0.53) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL9002738 | 0.83 | CASP1 (0.53) | — | |
| SCHEMBL18359408 | 0.80 | MEN1 (0.58) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL10487573 | 0.80 | MEN1 (0.58) | CTSKCTSLCTSBCTSSMEN1 | |
| SCHEMBL7323530 | 0.79 | ELANE (0.69) | CTSKCTSLCTSBCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092942-B1 | PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4472383-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0057998-B1 | ALICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-08-08 | — | — | EP | disclosed |
| EP-0092942-A2 | Peptide derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0057998-A1 | Alicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |