SCHEMBL10487589

SCHEMBL10487589

Cc1ccc(N(CC(=O)O)C(=O)[C@H](C)N)cc1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.49
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10487587 1.00 MLYCD (0.49) MLYCDKEAP1NFE2L2
SCHEMBL6047685 0.87 MLYCD (0.48) MLYCD
SCHEMBL14690329 0.87 MLYCD (0.48) MLYCD
SCHEMBL10487673 0.84 MLYCD (0.44) MLYCD
SCHEMBL10487678 0.84 MLYCD (0.44) MLYCD
SCHEMBL10537885 0.78 KEAP1 (0.51) KEAP1NFE2L2
SCHEMBL10881862 0.77 MLYCD (0.40) MLYCD
SCHEMBL10487690 0.75 MLYCD (0.41) MLYCD
SCHEMBL28110901 0.74 MLYCD (0.46) MLYCD
SCHEMBL10425651 0.74 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4820729-A N-substituted-amido-amino acids RORER PHARMACEUTICAL CORPORATION (US) 1989-04-11 US disclosed