Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30354041 | 1.00 | HTR6 (0.36) | HTR6HTR7HTR1AROCK2MAPT | |
| SCHEMBL21331779 | 0.84 | HTR6 (0.39) | HTR6ROCK2MAPTALDH1A1MEN1 | |
| SCHEMBL2296753 | 0.81 | NPSR1 (0.33) | HTR6HTR7HTR1AROCK2MAPT | |
| SCHEMBL1790973 | 0.79 | ALDH1A1 (0.37) | HTR7HTR1AROCK2NPSR1ALDH1A1 | |
| SCHEMBL3129527 | 0.79 | HTR6 (0.36) | HTR6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4730882 | 0.79 | ROCK2 (0.51) | HTR6HTR7HTR1AROCK2MAPT | |
| SCHEMBL31087066 | 0.78 | TSHR (0.35) | HTR6HTR7HTR1AMAPTALDH1A1 | |
| SCHEMBL29778140 | 0.78 | CYP2A6 (0.48) | ROCK2NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2628567 | 0.77 | ROCK2 (0.38) | HTR6ROCK2MAPTNPSR1ALDH1A1 | |
| SCHEMBL31581246 | 0.77 | MAPT (0.38) | HTR7HTR1AROCK2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737301-B2 | Preparation of 2-bicyclopropyl-2-yl-phenylamine through catalyzing the dehydrochlorination in the presence of a palladium complex; cost efficiency; used as intermediates for the preparation of fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-15 | — | — | US | claimed |
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | claimed |
| EP-1931618-B1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | claimed |
| EP-1931618-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2008-06-18 | — | — | EP | claimed |
| WO-2007025693-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-03-08 | — | — | WO | claimed |
| US-8785007-B2 | Pendant-type polymeric compound, color conversion film using pendant-type polymeric compound, and multicolor emission organic EL device | ADEKA CORPORATION (JP) | 2014-07-22 | — | — | US | disclosed |
| EP-2560960-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8519151-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-27 | — | — | US | disclosed |
| US-8519152-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2316813-B1 | Process for the preparation of amines | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-03 | — | — | EP | disclosed |
| EP-2269993-B1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1931618-B1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| EP-1581467-A4 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INST TECHNOLOGY (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1931618-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007025693-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-03-08 | — | — | WO | disclosed |
| EP-1581467-A2 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004052939-A2 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | CBR3, C1S, C9 | HTR6 3838/4885HTR7 2974/4885HTR1A 2460/4885 |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | DDT, TET1, TET3 | HTR6 1916/4885HTR7 3428/4885HTR1A 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.