Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487697 | 0.90 | KMT2A (0.49) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL10487679 | 0.88 | ALDH1A1 (0.51) | KMT2AMEN1MAPTKDM4EESR1 | |
| SCHEMBL10487798 | 0.87 | ESR1 (0.53) | KMT2AMEN1MAPTKDM4EESR1 | |
| SCHEMBL10608618 | 0.85 | GAA (0.51) | MAPTALDH1A1HCAR3 | |
| SCHEMBL3554130 | 0.84 | TPMT (0.51) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL10877944 | 0.84 | KMT2A (0.46) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL29407123 | 0.80 | VCAM1 (0.51) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL28690833 | 0.80 | VCAM1 (0.51) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL8841189 | 0.79 | VCAM1 (0.50) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL4199372 | 0.79 | VCAM1 (0.50) | KMT2AMEN1RXFP1VCAM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206635-B1 | PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4835306-A | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |