Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609093 | 0.90 | KMT2A (0.49) | KMT2AMEN1RXFP1MAPTPOLB | |
| SCHEMBL10610684 | 0.88 | ALDH1A1 (0.51) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL10607192 | 0.87 | ESR1 (0.53) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL22121312 | 0.85 | KMT2A (0.47) | KMT2AMEN1RXFP1MAPTPOLB | |
| SCHEMBL10606736 | 0.85 | GAA (0.51) | KMT2AMEN1MAPTPOLBKDM4E | |
| SCHEMBL645817 | 0.84 | VCAM1 (0.55) | KMT2AMEN1RXFP1MAPTPOLB | |
| SCHEMBL10487640 | 0.84 | KMT2A (0.46) | KMT2AMEN1RXFP1MAPTVCAM1 | |
| SCHEMBL3554130 | 0.84 | TPMT (0.51) | KMT2AMEN1RXFP1MAPTPOLB | |
| SCHEMBL22081923 | 0.80 | MAPT (0.52) | KMT2AMEN1RXFP1MAPTPOLB | |
| SCHEMBL30159180 | 0.80 | MAPT (0.52) | KMT2AMEN1RXFP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |