Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837578 | 0.93 | NFE2L2 (0.47) | NFE2L2ESR1ESR2 | |
| SCHEMBL9837901 | 0.92 | NFE2L2 (0.50) | NFE2L2ESR1ESR2 | |
| SCHEMBL10379791 | 0.75 | NFE2L2 (0.38) | NFE2L2ESR1ESR2 | |
| SCHEMBL28429862 | 0.72 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL9838977 | 0.71 | KDM4E (0.38) | NFE2L2 | |
| SCHEMBL9838822 | 0.71 | NFE2L2 (0.39) | NFE2L2ESR1ESR2 | |
| SCHEMBL9838929 | 0.70 | KDM4E (0.40) | NFE2L2 | |
| SCHEMBL9839149 | 0.70 | NFE2L2 (0.41) | NFE2L2ESR1ESR2 | |
| SCHEMBL10379530 | 0.69 | NFE2L2 (0.46) | NFE2L2 | |
| SCHEMBL10378485 | 0.68 | NFE2L2 (0.49) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847295-A | ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-07-11 | — | — | US | disclosed |