SCHEMBL10692661

SCHEMBL10692661

CC(CO)(COS(C)(=O)=O)NCc1c2ccccc2c(OCCO)c2c(Cl)cccc12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.33
SLC2A1 P11166 1/20 0.33
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10488421 0.91 SLC2A1 (0.39) MCL1SLC2A1CD274
SCHEMBL10692655 0.91 SLC2A1 (0.39) MCL1SLC2A1CD274
SCHEMBL10488423 0.91 SLC2A1 (0.39) MCL1SLC2A1CD274
SCHEMBL10488225 0.88 CD274 (0.37) MCL1SLC2A1CD274
SCHEMBL10488335 0.82 SLC2A1 (0.36) SLC2A1CD274
SCHEMBL10488880 0.81 SLC2A1 (0.38) SLC2A1CD274
SCHEMBL10488353 0.80 SLC2A1 (0.37) MCL1SLC2A1CD274
SCHEMBL10488281 0.78 SLC2A1 (0.37) SLC2A1CD274
SCHEMBL10488657 0.78 SLC2A1 (0.40) SLC2A1CD274
SCHEMBL10492815 0.77 SLC2A1 (0.42) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4719049-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed