SCHEMBL10488382

SCHEMBL10488382

COc1ccc(N=N)c(S(=O)(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
MPL P40238 1/20 0.40
MAPT P10636 1/20 0.38
ERN1 O75460 1/20 0.38
PKM P14618 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA2 P00918 2/20 0.37
PRKAB2 O43741 1/20 0.36
PRKAG1 P54619 1/20 0.36
PRKAA2 P54646 1/20 0.36
PRKAA1 Q13131 1/20 0.36
PRKAG3 Q9UGI9 1/20 0.36
PRKAG2 Q9UGJ0 1/20 0.36
PRKAB1 Q9Y478 1/20 0.36
CA1 P00915 1/20 0.36
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10488378 0.83 L3MBTL1 (0.41) L3MBTL1MPLMAPTPKMSMN1; SMN2
SCHEMBL12052698 0.82 MPL (0.42) L3MBTL1MPLMAPTPKMPRKAB2
SCHEMBL10488397 0.77 MPL (0.40) L3MBTL1MPLMAPT
SCHEMBL158763 0.77 L3MBTL1 (0.45) L3MBTL1MPLMAPTPKMSMN1; SMN2
SCHEMBL1817467 0.75 PKM (0.55) L3MBTL1MPLPKMSMN1; SMN2CA2
SCHEMBL30965843 0.75 L3MBTL1 (0.64) L3MBTL1MAPTSMN1; SMN2CA2CA1
SCHEMBL668653 0.75 L3MBTL1 (0.64) L3MBTL1MAPTSMN1; SMN2CA2CA1
SCHEMBL8300776 0.75 POLB (0.49) L3MBTL1MPLMAPTPKMSMN1; SMN2
SCHEMBL2336447 0.75 ERN1 (0.50) L3MBTL1MPLMAPTERN1PKM
SCHEMBL14546746 0.75 TDP1 (0.46) L3MBTL1MPLMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247193-B2 Ink, ink set, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-24 US disclosed
EP-0179549-B1 WATER-SOLUBLE DYE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-23 EP disclosed
US-4799960-A JET PRINTING; METALLIZED AZO DYES; WORKABILITY IN LIQUID MEDIUM CANON KABUSHIKI KAISHA (JP) 1989-01-24 US disclosed
US-4705528-A Water-soluble triazine black dyes from cellulose reactive groups and suitable for use in inks IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-10 US disclosed
EP-0179549-A2 Water-soluble dye IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-30 EP disclosed