Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.57 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488407 | 0.81 | LMNA (0.79) | LMNAHTTKCNH2SMN1; SMN2NPC1 | |
| SCHEMBL15060630 | 0.80 | KAT8 (0.69) | LMNAKAT8HAO1PPARATHRA | |
| SCHEMBL29093731 | 0.78 | KAT8 (0.63) | KAT8PPARATHRATHRBMAPT | |
| SCHEMBL207699 | 0.78 | KAT8 (0.66) | LMNASMN1; SMN2KAT8PPARANPC1 | |
| SCHEMBL10488494 | 0.77 | LMNA (0.73) | LMNAHTTKCNH2SMN1; SMN2NPC1 | |
| SCHEMBL28252921 | 0.77 | KAT8 (0.73) | LMNAKAT8PPARATHRATHRB | |
| SCHEMBL9651410 | 0.77 | KAT8 (0.73) | HTTKAT8PPARAMAPTALDH1A1 | |
| SCHEMBL1577439 | 0.76 | HAO1 (0.79) | HAO1THRATHRBMAPTALDH1A1 | |
| SCHEMBL10488403 | 0.76 | LMNA (1.00) | LMNAHTTKCNH2SMN1; SMN2NPC1 | |
| SCHEMBL29991001 | 0.76 | KAT8 (0.71) | LMNAKAT8PPARATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814162-A | SUNSCREENS | L'OREAL (FR) | 1989-03-21 | — | — | US | claimed |
| US-4814162-A | SUNSCREENS | L'OREAL (FR) | 1989-03-21 | — | — | US | disclosed |