Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.72 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.72 |
| ▸ | XBP1 | P17861 | 1/20 | 0.72 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488407 | 0.88 | LMNA (0.79) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL10488494 | 0.84 | LMNA (0.73) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL4828018 | 0.83 | RAB9A (0.71) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL12532243 | 0.81 | KMT2A (1.00) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL903310 | 0.80 | LMNA (0.66) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL29664124 | 0.80 | LMNA (0.66) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL12532247 | 0.78 | RAB9A (1.00) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL450084 | 0.78 | RAB9A (0.85) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL23093687 | 0.77 | LMNA (0.63) | LMNASMN1; SMN2HTTKCNH2MAPT | |
| SCHEMBL10488462 | 0.76 | LMNA (0.61) | LMNASMN1; SMN2HTTKCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814162-A | SUNSCREENS | L'OREAL (FR) | 1989-03-21 | — | — | US | claimed |
| US-4814162-A | SUNSCREENS | L'OREAL (FR) | 1989-03-21 | — | — | US | disclosed |