SCHEMBL10488472

SCHEMBL10488472

[N-]=[N+]=NS(=O)(=O)c1cc(N=Nc2ccc(N)cc2)ccc1C=Cc1ccc(N=Nc2ccc(N)cc2)cc1S(=O)(=O)N=[N+]=[N-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD51 Q06609 5/20 0.47
SENP2 Q9HC62 5/20 0.42
SENP1 Q9P0U3 5/20 0.42
SENP3 Q9H4L4 4/20 0.42
SUMO2 P61956 3/20 0.42
SUMO1 P63165 3/20 0.42
SENP7 Q9BQF6 3/20 0.42
CA12 O43570 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
MAPT P10636 5/20 0.39
TDP1 Q9NUW8 3/20 0.39
KDM4E B2RXH2 2/20 0.39
USP2 O75604 2/20 0.39
ALDH1A1 P00352 2/20 0.39
LTA P01374 2/20 0.39
CYP3A4 P08684 2/20 0.39
HPGD P15428 2/20 0.39
P2RX3 P56373 2/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10488457 1.00 RAD51 (0.47) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488930 0.86 RAD51 (0.47) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488933 0.86 RAD51 (0.47) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488780 0.83 RAD51 (0.44) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488783 0.83 RAD51 (0.44) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488400 0.80 ALDH1A1 (0.47) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488404 0.80 ALDH1A1 (0.47) RAD51SENP2SENP1SENP3SUMO2
SCHEMBL10488398 0.76 CA2 (0.58) CA12CA2CA9MAPTTDP1
SCHEMBL10488392 0.76 CA2 (0.58) CA12CA2CA9MAPTTDP1
SCHEMBL3090434 0.67 F2 (0.52) CA12CA2CA9TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4835089-A Resist pattern forming process with dry etching HITACHI, LTD. (JP) 1989-05-30 US claimed