Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670298 | 0.87 | EGFR (0.42) | SMPD1MEN1KMT2AHCRTR2MAOB | |
| SCHEMBL10706100 | 0.82 | MTNR1A (0.41) | RAF1MAP2K1SMPD1MEN1KMT2A | |
| SCHEMBL456296 | 0.82 | FOLH1 (0.43) | MAOBNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10477760 | 0.78 | MEN1 (0.47) | MEN1KMT2ABCHEMAOBACHE | |
| SCHEMBL11745909 | 0.77 | CYP19A1 (0.43) | SMPD1MEN1KMT2AHCRTR2NPC1 | |
| SCHEMBL10488086 | 0.77 | AR (0.42) | SMPD1BCHE | |
| Hydrochloric Acid SCHEMBL11670502 | 0.76 | EGFR (0.45) | SMPD1MEN1KMT2AHCRTR2NPC1 | |
| Hydrochloric Acid SCHEMBL11672815 | 0.76 | BRD4 (0.52) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL11750512 | 0.76 | CYP19A1 (0.44) | SMPD1MEN1KMT2AHCRTR2NPC1 | |
| SCHEMBL11669905 | 0.76 | EGFR (0.43) | SMPD1MEN1KMT2AHCRTR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |