Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488546 | 0.82 | RAF1 (0.38) | RAF1MAP2K1SMPD1KMT2ANPC1 | |
| SCHEMBL11824806 | 0.72 | HPGD (0.43) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL11826510 | 0.72 | HPGD (0.43) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL11670298 | 0.72 | EGFR (0.42) | SMPD1KMT2ANPC1MEN1PTPN1 | |
| SCHEMBL10917600 | 0.70 | NR4A2 (0.54) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL7109250 | 0.68 | NPC1 (0.48) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL7610813 | 0.68 | MAOB (0.56) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL5936603 | 0.67 | SMPD1 (0.56) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL11826519 | 0.66 | BRD4 (0.39) | SMPD1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL11824810 | 0.66 | FOLH1 (0.40) | SMPD1KMT2AKDM4ENPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |