SCHEMBL418270

SCHEMBL418270

CC(C)(C)C(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CES1 P23141 5/20 0.48
CES2 O00748 4/20 0.48
LMNA P02545 2/20 0.48
PGR P06401 1/20 0.46
ADRA2A P08913 1/20 0.46
ADRA2B P18089 1/20 0.46
HTR2A P28223 1/20 0.46
HRH1 P35367 1/20 0.46
KCNH2 Q12809 1/20 0.46
MDM2 Q00987 1/20 0.45
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 2/20 0.44
POLB P06746 2/20 0.44
TSHR P16473 4/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27531298 0.98 TDP1 (0.48) TDP1L3MBTL1CES1CES2LMNA
Acetophenone SCHEMBL10488608 0.92 SMN1; SMN2 (0.48) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL10789264 0.88 TDP1 (0.45) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL324099 0.86 CES2 (0.61) L3MBTL1CES1CES2LMNAALDH1A1
SCHEMBL1434697 0.82 TDP1 (0.50) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL8380017 0.82 MEN1 (0.53) TDP1LMNAPGRADRA2AADRA2B
SCHEMBL15658023 0.80 PGR (0.48) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL10444753 0.80 CES1 (0.52) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL11646755 0.79 TDP1 (0.44) TDP1L3MBTL1CES1CES2LMNA
SCHEMBL8251886 0.78 TDP1 (0.47) TDP1L3MBTL1CES1CES2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0982310-B1 Process for photostabilizing dibenzoylmethane-based sunscreens , cosmetic photostabilized sunscreen compositions obtained thereby, and their use OREAL (FR) 2004-03-31 EP claimed
EP-0752843-B1 ARTIFICIAL TANNING COMPOSITIONS HAVING IMPROVED COLOR DEVELOPMENT PROCTER & GAMBLE (US) 2000-12-06 EP claimed
EP-0714283-B1 PERSONAL CLEANSING COMPOSITIONS PROCTER & GAMBLE (US) 1999-05-12 EP claimed
EP-0752842-B1 ARTIFICAL TANNING COMPOSITIONS HAVING IMPROVED STABILITY PROCTER & GAMBLE (US) 1998-11-11 EP claimed
EP-0693920-B1 COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN AND PROTECTING THE SKIN FROM UV RADIATION PROCTER & GAMBLE (US) 1998-01-28 EP claimed
EP-0654989-B1 PHOTOSTABLE SUNSCREEN COMPOSITIONS PROCTER & GAMBLE (US) 1997-09-24 EP claimed
EP-0652774-B1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER PROCTER & GAMBLE (US) 1997-05-07 EP claimed
CN-107257679-A Personal nursing cream composition 荷兰联合利华有限公司 2017-10-17 CN disclosed
US-8828365-B2 Additive for UV-sunscreen preparations DSM IP ASSETS B.V. (NL) 2014-09-09 US disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 US disclosed
EP-1727515-B1 UV ABSORBING CHROMOPHORES COVALENTLY BONDED TO HYPERBRANCHED POLYMERS DSM IP ASSETS BV (NL) 2014-04-30 EP disclosed
US-20120282200-A1 UV ABSORBING DENTRITIC POLYETHER PREPARED BY POLYMERIZATION OF OXETANES DSM IP ASSETS B.V. (NL) 2012-11-08 US disclosed
EP-2510041-A1 UV ABSORBING DENTRITIC POLYETHER PREPARED BY POLYMERIZATION OF OXETANES DSM IP Assets B.V. (NL) 2012-10-17 EP disclosed
EP-0693920-B1 COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN AND PROTECTING THE SKIN FROM UV RADIATION PROCTER & GAMBLE (US) 1998-01-28 EP disclosed
EP-0654989-B1 PHOTOSTABLE SUNSCREEN COMPOSITIONS PROCTER & GAMBLE (US) 1997-09-24 EP disclosed
EP-0678015-B1 COSMETIC COMPOSITIONS CONTAINING SURFACE TREATED PIGMENTS PROCTER & GAMBLE (US) 1997-08-27 EP disclosed
EP-0652774-B1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER PROCTER & GAMBLE (US) 1997-05-07 EP disclosed
US-5468704-A Comprising titanium halide or halogen alcoholate supported on magnesium halide and a diketone electron donor; preparing polypropylene of high isotacticity MONTELL NORTH AMERICA INC. (US) 1995-11-21 US disclosed
CN-1105671-A Components and catalysts for olefin polymerization HIMONT INC (US) 1995-07-26 CN disclosed
EP-0646605-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120282200-A1 UV ABSORBING DENTRITIC POLYETHER PREPARED BY POLYMERIZATION OF OXETANES OGFOD1, OXGR1, DCLRE1A TDP1 3234/4885L3MBTL1 3614/4885CES1 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.