SCHEMBL324099

SCHEMBL324099

COc1ccc(C(=O)C(C(=O)c2ccccc2)C(C)(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.61
CES1 P23141 2/20 0.61
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
MAPT P10636 3/20 0.56
POLB P06746 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
ALDH1A1 P00352 2/20 0.53
CYP1A2 P05177 1/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
NPSR1 Q6W5P4 2/20 0.49
SLC2A1 P11166 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CDK5 Q00535 2/20 0.48
CDK5R1 Q15078 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418270 0.86 TDP1 (0.50) CES2CES1NPC1RAB9AMAPT
SCHEMBL10457519 0.84 CES2 (0.57) CES2CES1NPC1RAB9AMAPT
Methyl Alcohol SCHEMBL27531298 0.84 TDP1 (0.48) CES2CES1NPC1RAB9AMAPT
SCHEMBL4197237 0.82 CES2 (0.69) CES2CES1NPC1RAB9AMAPT
SCHEMBL15562904 0.81 CES2 (0.62) CES2CES1NPC1RAB9AMAPT
SCHEMBL29589535 0.81 CES2 (0.67) CES2CES1NPC1RAB9AMAPT
SCHEMBL8736770 0.81 CES2 (0.67) CES2CES1NPC1RAB9AMAPT
SCHEMBL8736772 0.81 CES2 (0.67) CES2CES1NPC1RAB9AMAPT
SCHEMBL7162385 0.80 MAPT (0.60) CES2CES1NPC1RAB9AMAPT
Acetophenone SCHEMBL10488608 0.79 SMN1; SMN2 (0.48) CES2CES1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound L'OREAL (FR) 2022-05-31 US claimed
US-8535648-B2 Stabilization of UV-sensitive active ingredients BASF SE (DE) 2013-09-17 US claimed
WO-2009020676-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS HALLSTAR INNOVATIONS CORP. (US) 2009-02-12 WO claimed
US-5605704-A HAIR TREATMENT WITH A CATIONIC LIPOSOMAL DISPERSION, CONSISTS OF CETYL TRIMETHYLAMMONIUM SALT AS CATIONIC SURFACTANT, CHOLESTEROL, SUNSCREEN AND ANTI-DANDRUFF AGENTS CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1997-02-25 US claimed
EP-0419164-B1 Hair conditioning composition UNILEVER PLC (GB) 1994-11-30 EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 EP claimed
EP-0386898-B1 SHAMPOO COMPOSITION UNILEVER PLC (GB) 1993-09-01 EP claimed
EP-0419164-A1 Hair conditioning composition UNILEVER PLC (GB) 1991-03-27 EP claimed
EP-0386898-A1 Shampoo composition UNILEVER PLC (GB) 1990-09-12 EP claimed
JP-9136822-A None JP disclosed
US-20240058235-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CLAY, AT LEAST ONE CRYSTALLIZABLE FATTY COMPOUND AND AT LEAST ONE LIPOSOLUBLE UV FILTER L'OREAL (FR) 2024-02-22 US disclosed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP disclosed
EP-2591082-B1 COMPOSITIONS COMPRISING OPTICAL BENEFIT AGENTS UNILEVER PLC (GB) 2020-11-18 EP disclosed
WO-2020067561-A1 OIL-IN-WATER TYPE SUNSCREEN COSMETIC 花王株式会社 2020-04-02 WO disclosed
EP-0604249-A1 Compositions containing dihydroxyacetone and their cosmetic use L'OREAL (FR) 1994-06-29 EP disclosed
EP-0386898-B1 SHAMPOO COMPOSITION UNILEVER PLC (GB) 1993-09-01 EP disclosed
US-5186928-A Anionic surfactant, water-insoluble sunscreen, and cationic derivative of polygalactomannan gum CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-02-16 US disclosed
EP-0468703-A1 Shampoo system UNILEVER PLC (GB) 1992-01-29 EP disclosed
EP-0419164-A1 Hair conditioning composition UNILEVER PLC (GB) 1991-03-27 EP disclosed
EP-0386898-A1 Shampoo composition UNILEVER PLC (GB) 1990-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058235-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CLAY, AT LEAST ONE CRYSTALLIZABLE FATTY COMPOUND AND AT LEAST ONE LIPOSOLUBLE UV FILTER FABP4, CUTA, PLIN3 CES2 1144/4885CES1 319/4885NPC1 1039/4885
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound DDT, ERCC5, ERCC1 CES2 4415/4885CES1 4582/4885NPC1 2200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.