Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488832 | 0.86 | MAPT (0.61) | MAPTGAAKDM4EPKMSHMT2 | |
| SCHEMBL10488595 | 0.84 | MAPT (0.57) | MAPTGAAKDM4EPKMCSNK2A1 | |
| SCHEMBL9006219 | 0.81 | GAA (0.62) | MAPTGAAPKMALDH1A1NPC1 | |
| SCHEMBL10488556 | 0.76 | KMT2A (0.59) | MAPTGAAALDH1A1ALPLMEN1 | |
| SCHEMBL10488648 | 0.73 | RAB9A (0.48) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL10488910 | 0.73 | PDGFRB (0.42) | MAPTGAAKDM4EALDH1A1ALPL | |
| SCHEMBL10488504 | 0.72 | KMT2A (0.57) | MAPTCSNK2A1ALDH1A1MEN1KMT2A | |
| SCHEMBL8834053 | 0.72 | AKR1C3 (0.63) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL1961624 | 0.71 | AKR1C3 (0.62) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5833241 | 0.71 | ALDH1A1 (0.73) | MAPTGAAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871737-A | 3-Amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4826866-A | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-02 | — | — | US | disclosed |