Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526225 | 0.81 | L3MBTL1 (0.55) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL5434789 | 0.77 | MAPT (0.61) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL29488187 | 0.77 | MAPT (0.61) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL4210466 | 0.75 | KMT2A (0.62) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL7349 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL29573636 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL23220327 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL5430219 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL29488194 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL15165726 | 0.73 | MAPT (0.56) | ALDH1A1MAPTLMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871737-A | 3-Amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4826866-A | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-02 | — | — | US | disclosed |