Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434789 | 1.00 | MAPT (0.61) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL29522293 | 0.87 | L3MBTL1 (0.70) | MAPTALDH1A1LMNAKDM4EEPHX1 | |
| SCHEMBL1276741 | 0.87 | L3MBTL1 (0.70) | MAPTALDH1A1LMNAKDM4EEPHX1 | |
| SCHEMBL27938801 | 0.85 | EPHX1 (0.57) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL9059553 | 0.82 | EPHX1 (0.62) | MAPTALDH1A1LMNAKDM4EEPHX1 | |
| SCHEMBL6835353 | 0.80 | EPHX1 (0.61) | MAPTALDH1A1LMNAKDM4EEPHX1 | |
| SCHEMBL194142 | 0.79 | ALDH1A1 (0.66) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL29998429 | 0.79 | ALDH1A1 (0.66) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL15165675 | 0.79 | LMNA (0.54) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL11598073 | 0.78 | ALDH1A1 (0.75) | MAPTALDH1A1LMNAKDM4EEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086079-A1 | DERIVATIVE OF SEMICARBAZONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | 고려대학교 산학협력단 | 2022-04-28 | — | — | WO | disclosed |