SCHEMBL10489259

SCHEMBL10489259

CCOP(=O)(O)c1ccccc1.N=C=O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
LMNA P02545 1/20 0.48
ACHE P22303 1/20 0.47
KCNH2 Q12809 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
AOX1 Q06278 1/20 0.44
POLB P06746 2/20 0.44
NPSR1 Q6W5P4 1/20 0.43
NR1I2 O75469 1/20 0.42
HIF1A Q16665 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344619 0.91 ACHE (0.55) ALDH1A1LMNAACHEKCNH2MEN1
Hydrochloric Acid SCHEMBL10824665 0.89 ACHE (0.53) ALDH1A1LMNAACHEKCNH2MEN1
Fluoride SCHEMBL29262354 0.89 ACHE (0.53) ALDH1A1LMNAACHEKCNH2MEN1
Butane SCHEMBL10939785 0.87 MEN1 (0.52) ALDH1A1LMNAACHEKCNH2MEN1
SCHEMBL11139451 0.78 AOX1 (0.43) ALDH1A1ACHEMEN1KMT2AAOX1
SCHEMBL28091784 0.77 ACHE (0.49) ALDH1A1LMNAACHEKCNH2MEN1
SCHEMBL12229770 0.77 MEN1 (0.47) ALDH1A1LMNAACHEMEN1KMT2A
SCHEMBL343472 0.77 MEN1 (0.67) ALDH1A1LMNAACHEMEN1KMT2A
SCHEMBL28968016 0.76 MEN1 (0.53) ALDH1A1LMNAACHEKCNH2MEN1
SCHEMBL15732278 0.75 CA2 (0.52) ALDH1A1LMNAMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4839254-A Photosensitive mixture and photosensitive recording material produced therefrom with polymeric binder which is reaction product of (thio) phosphinic acidiso (thio) cyanate and active hydrogen containing polymer HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-13 US disclosed