Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341723 | 0.75 | NQO1 (0.56) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL13034122 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL9559840 | 0.72 | NQO1 (0.56) | ALDH1A1KMT2AMEN1CYP1A2TDP1 | |
| SCHEMBL3234922 | 0.71 | NQO1 (0.61) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL10588253 | 0.70 | NQO1 (0.67) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL6277365 | 0.70 | NQO1 (0.67) | ALDH1A1KMT2AMEN1CYP1A2TDP1 | |
| SCHEMBL11760446 | 0.70 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNAPARP10GAA | |
| SCHEMBL28298039 | 0.70 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL11746967 | 0.70 | KMT2A (0.68) | ALDH1A1KMT2ALMNANQO1PARP10 | |
| SCHEMBL10587775 | 0.69 | NQO1 (0.64) | ALDH1A1KMT2AMEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883789-A | Substituted phenyltrialkylsilane insecticides | FMC CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| US-4709068-A | NONTOXIC TO FISH | FMC CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |