Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 6/20 | 0.48 |
| ▸ | BID | P55957 | 5/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 4/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489802 | 0.96 | PPARA (0.54) | PPARAPPARGFAAHBIDMCL1 | |
| SCHEMBL10489875 | 0.95 | PPARA (0.56) | PPARAPPARGFAAHBIDMCL1 | |
| SCHEMBL10489704 | 0.92 | TRPV1 (0.45) | PPARAPPARGFAAHTRPV1NPC1 | |
| SCHEMBL10489876 | 0.88 | RAB9A (0.50) | FAAHTRPV1NPC1RAB9ANPSR1 | |
| SCHEMBL10489696 | 0.87 | PPARA (0.56) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489844 | 0.85 | BID (0.50) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489834 | 0.84 | PPARA (0.49) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489749 | 0.84 | SMN1; SMN2 (0.54) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489767 | 0.83 | PPARA (0.61) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489872 | 0.83 | NPC1 (0.55) | PPARAPPARGBIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |