Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | BID | P55957 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.53 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.53 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.53 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.50 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489875 | 0.99 | PPARA (0.56) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489667 | 0.96 | PPARA (0.49) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489704 | 0.91 | TRPV1 (0.45) | PPARAPPARGFAAHKDM4EMAPT | |
| SCHEMBL10489767 | 0.87 | PPARA (0.61) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489876 | 0.87 | RAB9A (0.50) | FAAHKDM4EMAPT | |
| SCHEMBL10489676 | 0.86 | PPARA (0.64) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489933 | 0.85 | BID (0.56) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489829 | 0.84 | BID (0.54) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489797 | 0.84 | BID (0.54) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL10489927 | 0.84 | BID (0.58) | PPARAPPARGBIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |