Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670358 | 0.85 | NPC1 (0.45) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL7770602 | 0.85 | NPC1 (0.45) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL8383667 | 0.80 | TP53 (0.41) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL4907279 | 0.80 | TP53 (0.41) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL11793042 | 0.79 | TRPA1 (0.42) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL989084 | 0.79 | MEN1 (0.41) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL10489563 | 0.75 | IDO1 (0.50) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL8057322 | 0.74 | HTR2A (0.42) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL17836905 | 0.74 | RELA (0.53) | LMNATP53CYP2D6HSD17B10NPC1 | |
| SCHEMBL60042 | 0.74 | RELA (0.53) | LMNATP53CYP2D6HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847332-A | USING A VINYL-FUNCTIONAL ALCOHOL AS A PROPAGATOR FOR THE CATIONIC RING-OPENING POLYMERIZATION OF CYCLIC FORMALS; GRAFT AND COMB POLYMERS | THE B. F. GOODRICH COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4791189-A | USING PRIMARY OR SECONDARY UNSATURATED ALCOHOLS AS PROPAGATORS AND OXONIUM OR ETHERATE CATALYSTS; POLYESTERETHERS; BLOCK AND COMB POLYMERS | THE B. F. GOODRICH COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0291761-A2 | Terminally unsaturated macromolecular monomers of polylactones and copolymers thereof | THE B.F. GOODRICH COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |