Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661432 | 1.00 | NAMPT (0.42) | NAMPTAPPHTR6HTR2AHTR2C | |
| SCHEMBL10490374 | 0.84 | HSD17B10 (0.50) | APPHSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL4661227 | 0.79 | MEN1 (0.42) | APPHSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL4661438 | 0.74 | HTR6 (0.45) | NAMPTHTR6HTR2AHTR2CHSD17B10 | |
| SCHEMBL4664189 | 0.73 | TYMS (0.46) | HTR6HTR2AHTR2CKCNH2ALDH1A1 | |
| SCHEMBL12859084 | 0.71 | HSD17B10 (0.53) | HSD17B10POLBHPGDL3MBTL1MAPT | |
| SCHEMBL9080937 | 0.71 | CYP3A4 (0.57) | NAMPTHTR6HSD17B10ALDH1A1POLB | |
| SCHEMBL15015553 | 0.70 | ITGB3 (0.41) | HSD17B10ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL28941489 | 0.70 | HTR2A (0.64) | HTR6HTR2AHTR2CKCNH2POLB | |
| SCHEMBL24589993 | 0.69 | HTR6 (0.56) | HTR6ALDH1A1POLBHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |