Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295912 | 0.76 | MEN1 (0.50) | LMNASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL27341303 | 0.74 | HTT (0.51) | KDM4ELMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL4812903 | 0.73 | KDM4E (0.47) | KDM4ELMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL613262 | 0.72 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL9501505 | 0.70 | MEN1 (0.48) | KDM4ELMNASMN1; SMN2GLACHRNA7 | |
| SCHEMBL16872887 | 0.69 | NPC1 (0.51) | KDM4ELMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL14110027 | 0.69 | KDM4E (0.46) | KDM4ELMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11660620 | 0.68 | POLB (0.41) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9503355 | 0.68 | MEN1 (0.71) | GLA | |
| SCHEMBL10630917 | 0.67 | LMNA (0.75) | KDM4ELMNASMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4866113-A | COLORING POLYMERS | SANDOZ LTD. (CH) | 1989-09-12 | — | — | US | disclosed |
| US-4838943-A | Compounds useful as pigments containing one or more 2,2,6,6-tetraalkylpiperidine groups | SANDOZ LTD. (CH) | 1989-06-13 | — | — | US | disclosed |