Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23104383 | 0.80 | HRH3 (0.59) | HRH3NOS2NOS1NOS3 | |
| SCHEMBL29736634 | 0.80 | HRH3 (0.59) | HRH3NOS2NOS1NOS3 | |
| Undecane SCHEMBL28275328 | 0.78 | KCNH2 (0.54) | MCHR1KCNH2NOS2NOS3TLR8 | |
| SCHEMBL10490457 | 0.78 | CNR1 (0.39) | HRH3KCNH2KDM4EALDH1A1CNR1 | |
| SCHEMBL3186724 | 0.75 | HRH3 (0.36) | HRH3KDM4EALDH1A1NOS1NOS3 | |
| SCHEMBL6471082 | 0.75 | DNM1 (0.36) | HRH3MCHR1KCNH2DNM1GPR84 | |
| SCHEMBL24230542 | 0.75 | HCRTR1 (0.40) | KCNH2KDM4EALDH1A1CNR1 | |
| SCHEMBL23595038 | 0.74 | HRH3 (0.74) | HRH3TLR8 | |
| SCHEMBL3225592 | 0.74 | NOS3 (0.42) | MCHR1CNR1NOS2NOS1NOS3 | |
| SCHEMBL11260775 | 0.73 | CYP2D6 (0.50) | KCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804747-A | NON-LINEAR OPTICAL ELEMENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-14 | — | — | US | disclosed |
| EP-0293093-A2 | Azo Compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-30 | — | — | EP | disclosed |
| EP-0220042-A2 | Azo compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-29 | — | — | EP | disclosed |