Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.36 |
| ▸ | HTR1B | P28222 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051032 | 0.88 | HTR1D (0.36) | HTR1DHTR1BKMT2AACHEMTNR1A | |
| SCHEMBL1050938 | 0.85 | HTR1D (0.37) | HTR1DHTR1BKMT2AACHEMTNR1A | |
| SCHEMBL1051771 | 0.83 | ACHE (0.33) | HTR1DHTR1BKMT2AACHEMTNR1A | |
| SCHEMBL1051390 | 0.82 | ACHE (0.34) | HTR1DHTR1BKMT2AACHEMTNR1A | |
| SCHEMBL1083534 | 0.81 | CASP1 (0.40) | HTR1DHTR1BKMT2AMTNR1AMTNR1B | |
| SCHEMBL4533872 | 0.79 | HTR1D (0.31) | HTR1DHTR1B | |
| SCHEMBL1049084 | 0.77 | KMT2A (0.38) | HTR1DHTR1BKMT2AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL5164080 | 0.75 | HTR1D (0.40) | HTR1DHTR1BKMT2AMTNR1AMTNR1B | |
| SCHEMBL3769416 | 0.75 | HTR1D (0.38) | HTR1DHTR1BMTNR1AMTNR1BTRPV1 | |
| SCHEMBL4539260 | 0.75 | HTR1D (0.38) | HTR1DHTR1BMTNR1AMTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868036-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-01-11 | — | — | US | disclosed |