Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL10399492 | 0.88 | POLB (0.53) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Hexanoate SCHEMBL11747038 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29703129 | 0.83 | TDP2 (0.59) | MEN1KMT2APOLBTDP2TTR | |
| SCHEMBL1260800 | 0.83 | TDP2 (0.59) | MEN1KMT2APOLBTDP2TTR | |
| SCHEMBL28312724 | 0.79 | TP53 (0.46) | POLBTP53TSHRPTPN11TTR | |
| SCHEMBL15875142 | 0.79 | TP53 (0.46) | POLBTP53TSHRPTPN11TTR | |
| SCHEMBL2239053 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2244114 | 0.75 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28064458 | 0.75 | PTPN11 (0.58) | TP53TSHRPTPN11PLA2G4BRARB | |
| SCHEMBL14472810 | 0.74 | POLB (0.46) | MEN1KMT2AALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808732-A | CHEMICAL INTERMEDIATES FOR HOMO AND COPOLYIMIDES | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| US-4677186-A | AMINO DICARBOXYLIC ACID MONOMERS, PROTECITVE COATINGS | CIBA-GEIGY CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4629685-A | PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES | CIBA-GEIGY CORPORATION (US) | 1986-12-16 | — | — | US | disclosed |