Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | TDP2 | O95551 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260800 | 0.91 | TDP2 (0.59) | POLBTDP2KMT2AMEN1TTR | |
| SCHEMBL29703129 | 0.91 | TDP2 (0.59) | POLBTDP2KMT2AMEN1TTR | |
| Butyl Chloride SCHEMBL10492137 | 0.88 | MEN1 (0.51) | POLBTDP2KDM4EALDH1A1HPGD | |
| Hexanoate SCHEMBL11747038 | 0.87 | ALDH1A1 (0.51) | POLBTDP2KDM4EALDH1A1HPGD | |
| SCHEMBL14472810 | 0.82 | POLB (0.46) | POLBTDP2ALDH1A1HPGDKMT2A | |
| Butane SCHEMBL11141899 | 0.79 | POLB (0.53) | POLBKDM4EALDH1A1HPGDKMT2A | |
| Diphenylether SCHEMBL11834259 | 0.79 | MAOA (0.69) | POLBTDP2KMT2ATTRPTPRC | |
| Butane SCHEMBL10492117 | 0.79 | HPGD (0.45) | POLBKDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL11719702 | 0.78 | KMT2A (0.69) | TDP2KDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL11348981 | 0.78 | KMT2A (0.52) | POLBKDM4EALDH1A1HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898806-A | IRBADIATING AND HEATING POLYAMIC ACIDS TO POLYIMIDES | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| US-4814233-A | PROTECTIVE FILMS, COVERTIBLE TO POLYIMIDES; TRI-OR TETRA-CARBOXYLIC ACIDS WITH BENZOPHENONE GROUPS AND DIAMINES | CIBA-GEIGY CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4696890-A | POLYIMIDES BY HEATING A PHOTOCROSSLINKED POLYAMIC ESTER | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |