Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | PRKACG | P22612 | 1/20 | 0.45 |
| ▸ | PRKACB | P22694 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | USP8 | P40818 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810326 | 0.82 | LCK (0.56) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL30003082 | 0.76 | LCK (0.51) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL23271650 | 0.76 | LCK (0.51) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL11765286 | 0.76 | MEN1 (0.62) | KMT2AMEN1POLBCACNA1BAPBA1 | |
| SCHEMBL9177813 | 0.75 | ESR1 (0.51) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL7451901 | 0.75 | CA1 (0.57) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL2252533 | 0.75 | CA1 (0.57) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL29173163 | 0.73 | ESR1 (0.67) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL10885799 | 0.71 | CA1 (0.53) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL2993382 | 0.71 | CA1 (0.53) | LCKPRKACAPRKACGPRKACBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | claimed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |