Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | TDP2 | O95551 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623346 | 0.85 | ALDH1A1 (0.55) | MEN1KMT2APOLBCACNA1BAPBA1 | |
| SCHEMBL30716831 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2APOLBCACNA1BAPBA1 | |
| SCHEMBL3134949 | 0.78 | MEN1 (0.47) | MEN1KMT2APOLBCACNA1BAPBA1 | |
| SCHEMBL9452620 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2APOLBCACNA1BAPBA1 | |
| SCHEMBL10494249 | 0.76 | LCK (0.46) | MEN1KMT2APOLBCACNA1BAPBA1 | |
| SCHEMBL29678361 | 0.75 | APAF1 (1.00) | MEN1KMT2APOLBAPAF1TDP2 | |
| SCHEMBL461648 | 0.75 | APAF1 (1.00) | MEN1KMT2APOLBAPAF1TDP2 | |
| Anthraquinone SCHEMBL30656132 | 0.73 | MEN1 (0.63) | MEN1KMT2APOLBAPAF1TDP2 | |
| Anthraquinone SCHEMBL11147007 | 0.73 | MEN1 (0.63) | MEN1KMT2APOLBAPAF1TDP2 | |
| SCHEMBL15765937 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2APOLBCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450281-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-10-22 | — | — | US | disclosed |
| US-9725425-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-9725425-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-9725425-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20070026398-A1 | Protein tyrosine phosphatase-prl-1 a a marker and therapeutic target for pancreatic cancer | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2007-02-01 | — | — | US | disclosed |
| US-4017639-A | 2-Hydroxy-3-nitro-1,4-naphthoquinones for the prophylaxis of certain allergies | BEECHAM GROUP LIMITED (GB) | 1977-04-12 | — | — | US | disclosed |
| US-4014907-A | ANTIALLERGENS | BEECHAM GROUP LIMITED (EN) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450281-B1 | Compounds and methods for treating cancer | USP8, USP2, NEDD8 | MEN1 2034/4885KMT2A 230/4885POLB 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.