Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | BHMT | Q93088 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341843 | 1.00 | LTA4H (0.49) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL2807590 | 1.00 | LTA4H (0.49) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL4957790 | 1.00 | LTA4H (0.49) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL3341838 | 1.00 | LTA4H (0.49) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL31170917 | 0.96 | LTA4H (0.46) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL30198622 | 0.96 | LTA4H (0.46) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL30797948 | 0.91 | GNPAT (0.46) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL29374714 | 0.90 | BACE1 (0.48) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL30408803 | 0.88 | PTPN1 (0.45) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL30317542 | 0.88 | BACE1 (0.43) | LTA4HMMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849541-A | Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof | GENERAL FOODS CORPORATION (US) | 1989-07-18 | — | — | US | disclosed |
| US-4774027-A | Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof | GENERAL FOODS CORPORATION (US) | 1988-09-27 | — | — | US | disclosed |