SCHEMBL2807590

SCHEMBL2807590

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nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.49
MME P08473 5/20 0.46
ACE P12821 1/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
DPP4 P27487 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
BHMT Q93088 1/20 0.40
SLC7A5 Q01650 1/20 0.39
ANPEP P15144 1/20 0.39
ECE1 P42892 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341843 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL10494263 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL4957790 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL3341838 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL31170917 0.96 LTA4H (0.46) LTA4HMMEACECPA1ACE2
SCHEMBL30198622 0.96 LTA4H (0.46) LTA4HMMEACECPA1ACE2
SCHEMBL30797948 0.91 GNPAT (0.46) LTA4HMMEACECPA1ACE2
SCHEMBL29374714 0.90 BACE1 (0.48) LTA4HMMEACECPA1ACE2
SCHEMBL30408803 0.88 PTPN1 (0.45) LTA4HMMEACECPA1ACE2
SCHEMBL30317542 0.88 BACE1 (0.43) LTA4HMMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-2207525-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT METHOD L'Oréal (FR) 2010-07-21 EP claimed
EP-2205201-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING A POLYCONDENSATE, POLYCONDENSATE AND COSMETIC TREATMENT METHOD L'Oreal (FR) 2010-07-14 EP claimed
WO-2009053594-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-04-30 WO claimed
WO-2009053587-A2 COMPOSITION CONTAINING A POLYCONDENSATE, POLYCONDENSATE AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-04-30 WO claimed
WO-2009053584-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING A POLYCONDENSATE, POLYCONDENSATE AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-04-30 WO claimed
CN-101237850-A Pharmaceutical composition containing indomethacin and/or acemetacin DROSSAPHARM AG (CH) 2008-08-06 CN claimed
US-4849541-A Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof GENERAL FOODS CORPORATION (US) 1989-07-18 US claimed
US-4781927-A Sweetening with l-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-11-01 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-4849541-A Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof GENERAL FOODS CORPORATION (US) 1989-07-18 US disclosed
US-4822635-A Sweetening with L-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1989-04-18 US disclosed
US-4781927-A Sweetening with l-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-11-01 US disclosed
US-4774027-A Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof GENERAL FOODS CORPORATION (US) 1988-09-27 US disclosed
EP-0199257-A2 L-Aminodicarboxylic acid esters and an edible composition containing same as sweeteners GENERAL FOODS CORPORATION (US) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 LTA4H 1117/4885MME 4682/4885ACE 4847/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA LTA4H 1107/4885MME 4814/4885ACE 4664/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA LTA4H 2060/4885MME 3736/4885ACE 4711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.