SCHEMBL4957790

SCHEMBL4957790

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nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.49
MME P08473 5/20 0.46
ACE P12821 1/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
DPP4 P27487 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
BHMT Q93088 1/20 0.40
SLC7A5 Q01650 1/20 0.39
ANPEP P15144 1/20 0.39
ECE1 P42892 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341843 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL10494263 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL2807590 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL3341838 1.00 LTA4H (0.49) LTA4HMMEACECPA1ACE2
SCHEMBL31170917 0.96 LTA4H (0.46) LTA4HMMEACECPA1ACE2
SCHEMBL30198622 0.96 LTA4H (0.46) LTA4HMMEACECPA1ACE2
SCHEMBL30797948 0.91 GNPAT (0.46) LTA4HMMEACECPA1ACE2
SCHEMBL29374714 0.90 BACE1 (0.48) LTA4HMMEACECPA1ACE2
SCHEMBL30408803 0.88 PTPN1 (0.45) LTA4HMMEACECPA1ACE2
SCHEMBL30317542 0.88 BACE1 (0.43) LTA4HMMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182519-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN IPSEN PHARMA S.A.S. (FR) 2024-06-06 US claimed
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 US claimed
EP-2599483-A1 4-Phenylbutyric acid formulation Lunamed AG (CH) 2013-06-05 EP claimed
US-20080213339-A1 Pharmaceutical Composition Containing Indometacin and/or Acemetacin DROSSAPHARM AG (CH) 2008-09-04 US claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
EP-0728419-A2 Ingestible containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers BIORESEARCH, INC. (US) 1996-08-28 EP claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
EP-0420539-A2 Synergistic sweetening compositions containing a dipeptide sweetening agent and hydrogenated starch hydrolysates and methods for preparing same WARNER-LAMBERT COMPANY (US) 1991-04-03 EP claimed
US-4849541-A Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof GENERAL FOODS CORPORATION (US) 1989-07-18 US claimed
US-4781927-A Sweetening with l-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-11-01 US claimed
EP-0256475-A2 L-Aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-02-24 EP claimed
EP-0034876-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-08-29 EP claimed
EP-4711004-A2 METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2026-03-18 EP disclosed
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 US disclosed
EP-4618952-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-09-24 EP disclosed
US-4399163-A ARTIFICIAL SWEETENERS PFIZER INC. (US) 1983-08-16 US disclosed
EP-0069811-A1 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1983-01-19 EP disclosed
EP-0034876-A2 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1981-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080213339-A1 Pharmaceutical Composition Containing Indometacin and/or Acemetacin ACE, IDO1, CMA1 LTA4H 773/4885MME 11/4885ACE 1/4885
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST MC4R, NPY4R, MC3R LTA4H 2562/4885MME 2376/4885ACE 2940/4885
US-20240182519-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN MC4R, MC3R, MC1R LTA4H 533/4885MME 584/4885ACE 3654/4885
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R LTA4H 1006/4885MME 183/4885ACE 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.