Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15652613 | 0.86 | ALDH1A1 (0.76) | ALDH1A1ALDH1A3MAPTSMN1; SMN2TSHR | |
| SCHEMBL12527303 | 0.85 | ALDH1A1 (0.74) | ALDH1A1ALDH1A3MAPTSMN1; SMN2TSHR | |
| SCHEMBL6110135 | 0.84 | ALDH1A1 (0.72) | ALDH1A1ALDH1A3MAPTTSHRKDM4E | |
| SCHEMBL28710426 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ALDH1A3TSHRFDPS | |
| SCHEMBL30358126 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ALDH1A3MAPTSMN1; SMN2TSHR | |
| SCHEMBL18155343 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ALDH1A3MAPTSMN1; SMN2TSHR | |
| SCHEMBL31303216 | 0.80 | ALDH1A1 (0.65) | ALDH1A1ALDH1A3MAPTKDM4EHPGD | |
| SCHEMBL12543909 | 0.79 | ALDH1A1 (0.64) | ALDH1A1ALDH1A3MAPTTSHRKDM4E | |
| SCHEMBL14835776 | 0.78 | ALDH1A1 (0.64) | ALDH1A1ALDH1A3MAPTSMN1; SMN2TSHR | |
| SCHEMBL4079761 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034125-B2 | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | L'OREAL S.A. (FR) | 2011-10-11 | — | — | US | claimed |
| EP-2205681-B1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | OREAL (FR) | 2011-08-31 | — | — | EP | claimed |
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | claimed |
| EP-2205681-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'Oreal (FR) | 2010-07-14 | — | — | EP | claimed |
| WO-2009040354-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL (FR) | 2009-04-02 | — | — | WO | claimed |
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | claimed |
| US-7056348-B2 | 5-aryl-1,3,3-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibers | WELLA AG (DE) | 2006-06-06 | — | — | US | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| EP-1227786-B1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AG (DE) | 2005-08-24 | — | — | EP | claimed |
| EP-1194118-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-09-15 | — | — | EP | claimed |
| US-6485529-B1 | Agent and method for coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | claimed |
| WO-2002085854-A1 | 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | WO | claimed |
| EP-1227786-A1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | Wella Aktiengesellschaft (DE) | 2002-08-07 | — | — | EP | claimed |
| EP-1194118-A1 | AGENT FOR COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2001085111-A1 | AGENT FOR COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | claimed |
| EP-1143923-A1 | AGENT AND METHOD FOR COLOURING FIBRES | Wella Aktiengesellschaft (DE) | 2001-10-17 | — | — | EP | claimed |
| WO-2001062219-A1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | claimed |
| WO-2001028507-A1 | AGENT AND METHOD FOR COLOURING FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2001-04-26 | — | — | WO | claimed |
| EP-1054657-A1 | AGENT FOR COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | claimed |
| WO-2000033799-A1 | AGENT FOR COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | KRT18, SQOR, TST | ALDH1A1 743/4885ALDH1A3 407/4885MAPT 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.