Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495583 | 0.86 | MAPT (0.65) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL10508154 | 0.85 | CYP1A2 (0.48) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL1149069 | 0.83 | PDE7A (0.53) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL10354302 | 0.81 | CYP1A2 (0.47) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL11092359 | 0.81 | PDE7A (0.53) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL12594166 | 0.81 | HSPB1 (0.57) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL28508933 | 0.80 | CYP1A2 (0.51) | HSPB1MAPTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL9171793 | 0.80 | CYP1A2 (0.64) | HSPB1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10495539 | 0.78 | L3MBTL1 (0.50) | MAPTL3MBTL1RAB9APOLBALDH1A1 | |
| SCHEMBL16479498 | 0.78 | MAPT (0.64) | HSPB1MAPTNPSR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863924-A | N-benzoyl urea compounds, antitumorous compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0226104-A2 | N-Benzoyl urea compounds, antitumorous compositions containing them, and process for their preparation | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |