Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 11/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495662 | 1.00 | ADORA3 (0.55) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9872633 | 0.88 | CYP3A4 (0.54) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9872624 | 0.88 | CYP3A4 (0.54) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9873204 | 0.85 | LMNA (0.57) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9873200 | 0.85 | LMNA (0.57) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9871869 | 0.82 | ADORA3 (0.67) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9871872 | 0.82 | ADORA3 (0.67) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9871528 | 0.82 | ADORA3 (0.57) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL9871535 | 0.82 | ADORA3 (0.57) | ADORA3LMNANR1I2PGRDRD3 | |
| SCHEMBL10495665 | 0.80 | LMNA (0.52) | ADORA3LMNANR1I2PGRDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801599-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | GLAXO S.P.A. (IT) | 1989-01-31 | — | — | US | disclosed |